Chlorella and Spirulina: Risks and Side Effects

Chlorella and Spirulina: Risks and Side Effects You Should Know About

Before you start these supplements, discuss their possible risks with your doctor to determine if you should take them, and for how long.

Both Chlorella and Spirulina May Contain Toxic Metals

“Some chlorella and spirulina supplements have been found to contain trace amounts of heavy metals like aluminum, mercury, nickel, and lead,” King says.

One study from Poland of 52 commercially available spirulina and chlorella supplements reported finding aluminum, manganese, strontium, and zinc in them, though they were within the European Union’s limits for toxic metals. And both organic and nonorganic products were found to be contaminated with small amounts or with residues of substances like caffeine and prescription medications such as metronidazole (Flagyl), carbamazepine (Tegretol), benzocaine, and tramadol (Ultram).

“The main health risks stem from contamination,” Abroon says. “Unregulated products may contain heavy metals, bacteria, or cyanotoxins that could be harmful if taken regularly.”

Contaminants can build up in your body and harm your kidneys, nervous system, and gastrointestinal tract, he adds. To avoid this, look for supplements that are third-party-tested.

Spirulina May Cause Liver Damage

One review suggested the potential of liver damage from spirulina. A Japanese case study linked spirulina use as a possible cause of hepatotoxicity (chemical-driven liver damage) in a 52-year-old man.

 On the other hand, a meta-analysis from Iran of seven randomized controlled trials found that chlorella actually lowered one liver enzyme (aspartate aminotransferase), a marker of liver damage.

“In practical terms, for most healthy adults, the risk of spirulina-related hepatotoxicity appears to be very low — it’s just not zero,” Abroon says. Plus, he notes that some findings suggest that certain algae supplements may support liver function (or at least not harm it in healthy people).

Spirulina May Produce Other Harmful Bacteria and Toxins

Repeated exposure to certain toxins in spirulina can strain the liver, limiting its ability to process toxins, says Abroon.

A study out of Greece of five store-bought spirulina products found they contained potentially harmful bacteria and toxins at levels that could cause someone to exceed recommended daily safety limits for microcystin toxin (which is 2400 nanograms for adults weighing about 130 pounds, a conversion based on the World Health Organization’s tolerable daily intake for the liver toxin microcystin-LR). This may be because spirulina is usually grown in open ponds outdoors that can be contaminated by other microorganisms that produce toxins, unlike spirulina itself.