LNP-based delivery of a Toll-like receptor 9 agonist elicits potent adjuvant effects and antitumor immunity

The success of therapeutic cancer vaccines hinges on overcoming the immunosuppressive tumor microenvironment (TME) and ...

Laser interstitial thermal therapy and adjuvant pembrolizumab in recurrent high-grade astrocytoma: a Phase 1/randomized Phase 2b trial

Study design and treatments Approval Human subject work was performed in accordance with an approved ...

Antigen cross-presentation potentiating cancer vaccine adjuvant for T cell expansion and synergy with anti-PD-1

Brandenburg, A., Heine, A. & Brossart, P. Next-generation cancer vaccines and emerging immunotherapy combinations. Trends ...