Phosphorylation of Runx protein controls helper CD4+ T cell versus cytotoxic CD8+ T cell lineage choice

Mice Runx1+/WRPW embryos were generated by incorporation single-strand donor DNA into the Runx1 locus by ...

STAT1 signaling controls cholesterol metabolism in epithelial cells and RSV-induced syncytia formation

Biallelic Knockout of STAT1 alters cellular cholesterol metabolism and homeostasis For the generation of a ...

Cohesin-mediated chromatin organization controls the differentiation and function of dendritic cells | Science Immunology

Chromatin-organizing cohesin complex cooperates with transcription factor IRF8 to enable the functionality of dendritic cells ...

STING controls glycolysis and histone lactylation to drive macrophage metabolic reprogramming in postoperative ileus

Vather, R., Trivedi, S. & Bissett, I. Defining postoperative ileus: results of a systematic review ...

Epidermal growth factor receptor controls sex differences in lung type 2 responses to inhaled allergen | Science Immunology

Female mice have exacerbated, EGFR-dependent lung type 2 immunity when exposed to inhaled house dust ...

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment

Study design This study aimed to evaluate whether organelle inheritance controls CD8+ T cell differentiation. ...