Tag: enhance

Fine-tuning BACH2 dosage balances stemness and effector function to enhance antitumor T cell therapy

Fine-tuning BACH2 dosage balances stemness and effector function to enhance antitumor T cell therapy

BACH2 overexpression locks T cells in a quiescent ineffective state We and others have shown ...

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BACH2 regulates T cell lineage state to enhance CAR T cell function

BACH2 regulates T cell lineage state to enhance CAR T cell function

Frigault, M. J. et al. Identification of chimeric antigen receptors that mediate constitutive or inducible ...

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Mesenchymal stromal cells counteract with age-related immune decline and enhance vaccine efficacy by modulating endogenous splenic marginal reticular cells in elderly models

Mesenchymal stromal cells counteract with age-related immune decline and enhance vaccine efficacy by modulating endogenous splenic marginal reticular cells in elderly models

Collier DA, Ferreira IATM, Kotagiri P, Datir RP, Lim EY, Touizer E, et al. Age-related ...

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Cis- and trans-binding chimeric costimulatory receptors enhance T-cell fitness and tumor control

Cis- and trans-binding chimeric costimulatory receptors enhance T-cell fitness and tumor control

Ledergor G, Fan Z, Wu K, McCarthy E, Hyrenius-Wittsten A, Starzinski A, et al. CD4+ ...

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Dietary restriction reprograms CD8+ T cell fate to enhance anti-tumour immunity and immunotherapy responses

Dietary restriction reprograms CD8+ T cell fate to enhance anti-tumour immunity and immunotherapy responses

Ethical compliance All research described in this study was conducted in accordance with relevant institutional ...

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