Tag: epigenetic

Epigenetic reprogramming of T cell metabolism restores function and enhances anti-tumor immunity in lung cancer

Epigenetic reprogramming of T cell metabolism restores function and enhances anti-tumor immunity in lung cancer

Wherry, E. J. & Kurachi, M. Molecular and cellular insights into T cell exhaustion. Nat. ...

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Foxp3: The epigenetic engineer of regulatory T cell identity | Science Immunology

Foxp3: The epigenetic engineer of regulatory T cell identity | Science Immunology

The Foxp3 transcription factor integrates cell-intrinsic and environmental contexts with epigenetic programs to establish regulatory ...

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Foxp3 drives context-dependent epigenetic programs that define regulatory T cell molecular identity and function | Science Immunology

Foxp3 drives context-dependent epigenetic programs that define regulatory T cell molecular identity and function | Science Immunology

Foxp3 integrates cell-intrinsic and environmental contexts with epigenetic programs to establish Treg cell molecular identity ...

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Weaning drives microbiome-mediated epigenetic regulation to shape immune memory in mice

Weaning drives microbiome-mediated epigenetic regulation to shape immune memory in mice

SPF and GF Lgr5-GFP mice We used a knock-in Lgr5EGFP−IRES−CreERT2 mouse model (Lgr5-GFP) in which ...

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