Chemokine-defined macrophage niches establish spatial organization of tumor immunity

RecMacs display protumor transcriptional signatures To identify macrophage subsets associated with tumor regression or progression, ...

Modulating AP-1 enables CAR T cells to establish an intratumoral stemlike reservoir and overcomes resistance to PD-1 blockade | Science Immunology

c-Jun overexpression fails to prevent CAR T cell exhaustion in tumors, but PD-L1 blockade restores ...