Tag: function

Cohesin-mediated chromatin organization controls the differentiation and function of dendritic cells | Science Immunology

Cohesin-mediated chromatin organization controls the differentiation and function of dendritic cells | Science Immunology

Chromatin-organizing cohesin complex cooperates with transcription factor IRF8 to enable the functionality of dendritic cells ...

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Why Strength Training Is Essential for Cognitive Function

Why Strength Training Is Essential for Cognitive Function

We all know that weightlifting is great for building muscle—and it has fantastic potential to ...

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Spatiotemporal regulation of energetic charge dictates T cell function

Spatiotemporal regulation of energetic charge dictates T cell function

Mice C57BL/6 J mice, aged 6 to 8 weeks, were purchased from ENVIGO and housed in ...

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Publisher Correction: SLC2A1+ tumour-associated macrophages spatially control CD8+ T cell function and drive resistance to immunotherapy in non-small-cell lung cancer

Publisher Correction: SLC2A1+ tumour-associated macrophages spatially control CD8+ T cell function and drive resistance to immunotherapy in non-small-cell lung cancer

These authors contributed equally: Lei Wang, Han Chu, Degao Chen, Yuxuan Wei. Department of Oncology, ...

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Cell cycle arrest enhances CD8+ T cell effector function by potentiating glucose metabolism and IL-2 signaling

Cell cycle arrest enhances CD8+ T cell effector function by potentiating glucose metabolism and IL-2 signaling

Enhanced CD8+ T cell proliferation after temporal cell cycle inhibition To uncouple CD8+ T cell ...

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Fine-tuning BACH2 dosage balances stemness and effector function to enhance antitumor T cell therapy

Fine-tuning BACH2 dosage balances stemness and effector function to enhance antitumor T cell therapy

BACH2 overexpression locks T cells in a quiescent ineffective state We and others have shown ...

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Betaine Supports Healthy Methylation & Cardiovascular Function*

Betaine Supports Healthy Methylation & Cardiovascular Function*

If you’re interested in heart health, you’re going to want to know about betaine. While ...

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BACH2 regulates T cell lineage state to enhance CAR T cell function

BACH2 regulates T cell lineage state to enhance CAR T cell function

Frigault, M. J. et al. Identification of chimeric antigen receptors that mediate constitutive or inducible ...

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PTMA safeguards mitochondrial integrity to sustain metabolic function and antitumor activity of CD8 T cells | Science Immunology

PTMA safeguards mitochondrial integrity to sustain metabolic function and antitumor activity of CD8 T cells | Science Immunology

The TCF1-PTMA axis maintains mitochondrial homeostasis to sustain CD8 T cell function and preserve immune ...

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The differentiation and function of heterogeneous thymic dendritic cell subsets require signals provided by distinct thymocyte cell types

The differentiation and function of heterogeneous thymic dendritic cell subsets require signals provided by distinct thymocyte cell types

Ashby, K. M. & Hogquist, K. A. A guide to thymic selection of T cells. ...

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