Tag: fusion

mRNA vaccination targeting AML1::ETO fusion gene eliminates leukemia cells via activating T cells

mRNA vaccination targeting AML1::ETO fusion gene eliminates leukemia cells via activating T cells

The t(8;21) translocation in AML generates the non-druggable RUNX1::RUNX1T1 (AML1::ETO; AE) fusion protein. Despite initial ...

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A cancer-promoting fusion protein acts during embryonic brain development

A cancer-promoting fusion protein acts during embryonic brain development

RESEARCH BRIEFINGS 25 March 2026 ZFTA–RELA is the cancer-promoting protein product of a gene fusion. ...

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