Tag: leukemia

Synergizing hypomethylating agents with off-the-shelf CD70-targeted chimeric antigen receptor-engineered natural killer T cells for the treatment of acute myeloid leukemia

Synergizing hypomethylating agents with off-the-shelf CD70-targeted chimeric antigen receptor-engineered natural killer T cells for the treatment of acute myeloid leukemia

HMAs upregulate CD70, CD1d, and NKR ligands on AML blasts We first confirmed that HMAs ...

READ MORE
Anti-thymocyte globulin (ATG)- or alemtuzumab-based graft-versus-host disease prophylaxis in reduced-intensity conditioning allogeneic hematopoietic cell transplantation (HCT) for patients 40 years and older with acute lymphoblastic leukemia in first complete remission: a study from the EBMT Acute Leukemia Working Party

Anti-thymocyte globulin (ATG)- or alemtuzumab-based graft-versus-host disease prophylaxis in reduced-intensity conditioning allogeneic hematopoietic cell transplantation (HCT) for patients 40 years and older with acute lymphoblastic leukemia in first complete remission: a study from the EBMT Acute Leukemia Working Party

Giebel S, Labopin M, Socie G, Beelen D, Browne P, Volin L, et al. Improving ...

READ MORE
Acute Myeloid Leukemia Survival Rates and Outlook

Acute Myeloid Leukemia Survival Rates and Outlook

Key Takeaways The five-year survival rate for people diagnosed with acute myeloid leukemia (AML) is ...

READ MORE
Characteristics and outcome determinants in children, adolescents and young adults who failed tisagenlecleucel for B-cell acute lymphoblastic leukemia

Characteristics and outcome determinants in children, adolescents and young adults who failed tisagenlecleucel for B-cell acute lymphoblastic leukemia

Maude SL, Frey N, Shaw PA, Aplenc R, Barrett DM, Bunin NJ, et al. Chimeric ...

READ MORE
What Is Chronic Lymphocytic Leukemia (CLL)?

What Is Chronic Lymphocytic Leukemia (CLL)?

Treatment for Chronic Lymphocytic Leukemia Your treatment will depend on how advanced your disease is, ...

READ MORE
CXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting

CXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting

CXCR4 marks CD4+ memory T cells associated with AML remission To identify features linked to ...

READ MORE
Leukemia Symptoms

Leukemia Symptoms

The symptoms you experience will depend on whether your disease is chronic or acute and ...

READ MORE
A T-cell receptor targeting RUNX1 frameshift mutations in acute myeloid leukemia

A T-cell receptor targeting RUNX1 frameshift mutations in acute myeloid leukemia

Döhner H, Wei AH, Appelbaum FR, Craddock C, DiNardo CD, Dombret H, et al. Diagnosis ...

READ MORE
Gene-edited CAR-T cells erase aggressive T-cell leukemia

Gene-edited CAR-T cells erase aggressive T-cell leukemia

A new treatment created by scientists at UCL (University College London) and Great Ormond Street ...

READ MORE