Naringin alleviates periodontitis via direct AMPK/Nrf2 activation and NLRP3 inhibition, amplified by gut microbiota/Arg-Gln modulation

Periodontitis, driven by oral-gut microbiota dysbiosis and NLRP3 inflammasome activation, lacks effective natural therapeutic strategies. ...

Regulatory mechanisms of ALKBH5/CIITA axis in the synergistic modulation of hepatocellular carcinoma radiotherapy and immunotherapy

Cell lines and culture In this research, the human normal liver cell line LO2, along ...

Intracellular complement Factor H promotes tumor progression through modulation of cell cycle and actin cytoskeleton

Borisov, T., Metodiev, D., Ferdinandov, D. & Roumenina, L. T. Complement system in tumor growth ...

Melatonin attenuates glandular cystitis via modulation of THBS1 and TLR4/p38 MAPK/STAT3 signaling

Regents LPS (ST1470-50 mg) was from Beyotime Biotechnology; MEL (A600605) was from Sangon Biotech (Shanghai) Co., ...

Multi-pathway regulatory role of miR-4693-5p in the modulation of rheumatoid arthritis

Sample collection Biopsy samples were collected from n = 12 RA-diagnosed individuals at the Orthopedic Department of ...