Tag: neutralizing

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development | Science Immunology

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development | Science Immunology

B cell priming is a primary bottleneck to HIV-1 V2 apex bNAb elicitation. ...

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Rapid elicitation of neutralizing Asn332-glycan-independent antibodies to the V3-glycan epitope of HIV-1 Env in nonhuman primates

Rapid elicitation of neutralizing Asn332-glycan-independent antibodies to the V3-glycan epitope of HIV-1 Env in nonhuman primates

Ethics and inclusion This research complies with all relevant ethical regulations (Tulane National Primate Research ...

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Identification of a potent V3 glycan site broadly neutralizing antibody targeting an N332gp120 glycan-independent epitope

Identification of a potent V3 glycan site broadly neutralizing antibody targeting an N332gp120 glycan-independent epitope

Study participants and collection of clinical samples Large blood draws and leukapheresis samples were collected ...

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Minor SHIV variants abrogate protective efficacy of broadly neutralizing antibodies in rhesus macaques

Minor SHIV variants abrogate protective efficacy of broadly neutralizing antibodies in rhesus macaques

Animals Animal studies were conducted with the approval of the appropriate Institutional Animal Care and ...

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Phosphorylated tau exhibits antimicrobial activity capable of neutralizing herpes simplex virus 1 infectivity in human neurons

Phosphorylated tau exhibits antimicrobial activity capable of neutralizing herpes simplex virus 1 infectivity in human neurons

3D human neuronal cell culture model + microglia GFP-expressing ReNcell VM neuronal cell line G10, ...

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