Single-immunocyte transcriptomics reveal the role of natural killer cell-dependent exogenous antigen presentation in ankylosing spondylitis severity

Single-immunocyte transcriptional profiling First, we conducted a scRNA-seq to investigate the transcriptomic characteristics of PBMCs ...

DNA damage in macrophages drives immune autoreactivity via nuclear antigen presentation

Animals Wild-type and Er1Lyz2/− mice were generated as previously described by intercrossing Lyz2–cre (C57BL/6 background), ...

Intratumoural vaccination via checkpoint degradation-coupled antigen presentation

Kalbasi, A. & Ribas, A. Tumour-intrinsic resistance to immune checkpoint blockade. Nat. Rev. Immunol. 20, ...

The emerging role of dendritic cells in the tumor microenvironment: from antigen presentation to targeted immunotherapy

Steinman RM, Cohn ZA. Identification of a novel cell type in peripheral lymphoid organs of ...