Reconstituting central nervous system niche cues partially restores homeostatic-like features in cultured murine primary microglia

In this study we showed that standard in vitro culture of primary mouse microglia precipitates ...

Living With Primary Biliary Cholangitis: 7 Ways to Prioritize Your Emotional Health

While you may be living with fatigue, itching, brain fog, and joint pain — symptoms ...

COVID-19 boosters restore virus-specific immune responses in kidney transplant recipients unresponsive to primary vaccination

Study design This in-depth immunological analysis was conducted on samples obtained from KTRs selected from ...

How to Minimize Infusion Anxiety in Adults and Children With Primary Immunodeficiency

As you work toward mastering SCIg, keep in mind that many people have had the ...

How to Plan for Successful Home SCIg Self-Administration for Primary Immunodeficiency

For many people, inserting the needle is the most intimidating part of home SCIg. The ...

IVIg to SCIg: Considerations When Switching Immunoglobulin Therapies for Primary Immunodeficiency

For people living with primary immunodeficiency (PI) , immunoglobulin replacement therapy (Ig) is a cornerstone ...

Metabolomic profiling reveals alterations in Candida pathophysiology and host interactions during primary oral candidiasis and following antifungal treatment

Millsop, J. W. & Fazel, N. Oral candidiasis. Clin. Dermatol. 34, 487–494 (2016). PubMed  Google ...

IgA-driven neutrophil activation underlies severe dengue disease after primary Zika virus infection in humans

Bhatt, S. et al. The global distribution and burden of dengue. Nature 496, 504–507 (2013). ...

The chaperone GRP94 interacts with the proprotein convertase furin and regulates TGF-beta maturation in human primary M2 macrophages

Human PBMC-derived macrophages obtention and cell culture Peripheral blood mononuclear cells (PBMC) were separated from ...