Reconstituting central nervous system niche cues partially restores homeostatic-like features in cultured murine primary microglia

In this study we showed that standard in vitro culture of primary mouse microglia precipitates ...

Epigenetic reprogramming of T cell metabolism restores function and enhances anti-tumor immunity in lung cancer

Wherry, E. J. & Kurachi, M. Molecular and cellular insights into T cell exhaustion. Nat. ...

DUSP6 ablation restores CAR T-cell fitness impaired by tumor CD58 loss through invigoration of AP-1 signaling

Cells and ethics The cell lines were purchased from ATCC (Manassas, VA) and cultured in ...