Tag: stemlike

Tissue-restricted secondary TCR engagement drives the transition from stem-like to CD200+ Egr2hi arthritogenic Th17 cells

Tissue-restricted secondary TCR engagement drives the transition from stem-like to CD200+ Egr2hi arthritogenic Th17 cells

McGeachy, M. J., Cua, D. J. & Gaffen, S. L. The IL-17 family of cytokines ...

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Modulating AP-1 enables CAR T cells to establish an intratumoral stemlike reservoir and overcomes resistance to PD-1 blockade | Science Immunology

Modulating AP-1 enables CAR T cells to establish an intratumoral stemlike reservoir and overcomes resistance to PD-1 blockade | Science Immunology

c-Jun overexpression fails to prevent CAR T cell exhaustion in tumors, but PD-L1 blockade restores ...

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