CD300ld on pathologically activated neutrophils promotes tumor immune suppression by binding phosphatidylserine on CD8+ T cells

Mao, Y. et al. The landscape of objective response rate of anti-PD-1/L1 monotherapy across 31 ...

Targeting the PSMD14-BCKDK pathway overcomes immune suppression and enhances CAR-NK infiltration in glioblastoma

Tumor cells outcompete NK cells for BCAA, with BCKDK as a key regulator Nutrient competition ...

Beyond suppression: the paradox of JAK inhibitors as amplifiers of cancer immunotherapy

Mumm, J. B. et al. IL-10 elicits IFNγ-dependent tumor immune surveillance. Cancer Cell 20, 781–796 ...

Inhibin beta A drives colorectal cancer progression through macrophage M2 polarization and mitochondria-dependent ferroptosis suppression

Ethics declarations The animal protocols received authorization from Hunan Cancer Hospital’s Institutional Animal Care and ...