Tag: Thymic

Unraveling CD8 lineage decisions reveals that functionally distinct CD8+ T cells are selected by different MHC-I thymic peptides

Unraveling CD8 lineage decisions reveals that functionally distinct CD8+ T cells are selected by different MHC-I thymic peptides

Littman, D. R. How thymocytes achieve their fate. J. Immunol. 196, 1983–1984 (2016). Article  PubMed  ...

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Artificial thymic organoid culture generates functional iPSC-derived CD4+ invariant natural killer T cells

Artificial thymic organoid culture generates functional iPSC-derived CD4+ invariant natural killer T cells

Zitvogel, L., Tesniere, A. & Kroemer, G. Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat. Rev. ...

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The differentiation and function of heterogeneous thymic dendritic cell subsets require signals provided by distinct thymocyte cell types

The differentiation and function of heterogeneous thymic dendritic cell subsets require signals provided by distinct thymocyte cell types

Ashby, K. M. & Hogquist, K. A. A guide to thymic selection of T cells. ...

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Damage-induced pyroptosis drives endogenous thymic regeneration by activating the purinergic receptor P2Y2

Damage-induced pyroptosis drives endogenous thymic regeneration by activating the purinergic receptor P2Y2

Kinsella S, Dudakov JA. When the damage is done: injury and repair in thymus function. ...

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