Tag: trial

Guinea-Bissau suspends a US-funded vaccine trial as African scientists question its motives

Guinea-Bissau suspends a US-funded vaccine trial as African scientists question its motives

Guinea-Bissau will implement a universal birth-dose policy for the Hepatitis B vaccine in 2027.Credit: Enrique ...

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Nous-209 neoantigen vaccine for cancer prevention in Lynch syndrome carriers: a phase 1b/2 trial

Nous-209 neoantigen vaccine for cancer prevention in Lynch syndrome carriers: a phase 1b/2 trial

Trial participants Our study population comprised individuals aged 18 years or older with a diagnosis of ...

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BCMA-directed mRNA CAR T cell therapy for myasthenia gravis: a randomized, double-blind, placebo-controlled phase 2b trial

BCMA-directed mRNA CAR T cell therapy for myasthenia gravis: a randomized, double-blind, placebo-controlled phase 2b trial

Oversight The MG-001 part 3 trial was performed in accordance with the principles of the ...

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BCMA-directed mRNA CAR-T cell therapy for myasthenia gravis: exploratory biomarker analysis of a placebo-controlled phase 2b trial

BCMA-directed mRNA CAR-T cell therapy for myasthenia gravis: exploratory biomarker analysis of a placebo-controlled phase 2b trial

Preclinical in vitro experiments Generation of CAR cells and evaluation of CAR expression Primary CD8+ ...

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Autoantibody landscape and functional role of anti-C-C motif chemokine receptor 8 autoantibodies in systemic sclerosis: post-hoc analysis of a B-cell depletion trial

Study design The study design for the DESIRES trial has been previously reported (NCT04274257)30. The ...

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