Investigating the effects and underlying mechanisms of glycosylation sites on the immunogenicity of COVID-19 vaccines

Removing N-glycosylation of the ZF2001 vaccine affects neutralizing antibody levels Neutralizing antibody titers in the ...

Tuning the immune response to mRNA vaccines

Tuning the immune response to mRNA vaccines ...

Venezuelan equine encephalitis virus: novel live-attenuated vaccines for inducing complete protective immunity

Forrester, N. L. et al. Evolution and spread of Venezuelan equine encephalitis complex alphavirus in ...

Lysosome-targeting live attenuated influenza vaccines elicit robust and broad immunity in mice

Viruses and vaccines Influenza A/WSN/33 (H1N1) and A/X-31 (H3N2) viruses were used in this study. ...

DNA origami vaccines could be the next leap beyond mRNA

The COVID-19 pandemic brought messenger RNA (mRNA) vaccines into the global spotlight. After completing clinical ...

Are Vaccines Required? Mandatory vs. Recommended Vaccines

Key Takeaways Vaccination rules vary from state to state. Employers may require vaccines but must ...

Gonococcal outer membrane vesicle vaccines: bacterial population biology, clinical trials, immune profiling, and vaccine design

Quillin, S. J. & Seifert, H. S. Neisseria gonorrhoeae host adaptation and pathogenesis. Nat. Rev. ...

Immunogenicity and protective efficacy of MERS CoV, NL140422, and HKU4 spike protein nanoparticle vaccines

Expression and purification of S antigens DNA constructs encoding MERS-CoV England-1 S with the 2 P ...

Conserved CD4+ T cell staphylococcal and streptococcal epitopes enable broad-acting vaccines in mice

GBD 2021 Antimicrobial Resistance Collaborators Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis ...

Harnessing mucosal immunity for protective vaccines

Thompson, M. G. et al. Effectiveness of Covid-19 vaccines in ambulatory and inpatient care settings. ...