What Happens to Your Blood Sugar When You Drink Orange Juice

What Happens to Your Blood Sugar When You Drink Orange Juice

Key Takeaways

  • Emerging evidence suggests that orange juice may have a neutral effect on blood sugar levels.
  • It has a low glycemic index, about 43 to 49.
  • Flavonoids, an antioxidant found in oranges and other plants, may contribute to the muted effect of orange juice on blood sugar.

Many people believe that drinking orange juice raises blood sugar levels. However, research shows that it has a more neutral effect.

How Orange Juice Affects Blood Sugar

Blood sugar (blood glucose) is the amount of sugar circulating in the blood. High and low blood sugar can lead to symptoms and progress to medical emergencies if left untreated.

Orange juice has a reputation for spiking blood sugar levels, mainly due to its high carbohydrate content and low fiber content. However, research on the topic has yielded mixed results.

Multiple studies have found that drinking orange juice doesn’t always affect blood sugar levels, and in some cases, it may even lower them slightly.

Scientists suggest that the natural sugars in orange juice do not affect blood sugar in the same way that refined sugar in sodas or other beverages does.

Orange juice also contains flavonoids, which are antioxidant compounds found in plants. One flavonoid, hesperidin, is associated with the ability to lower blood sugar, potentially explaining why orange juice does not significantly raise blood sugar levels, despite its carbohydrate content.

Orange Juice Glycemic Index

The glycemic index (GI) ranks carbohydrate-containing foods by how quickly they can raise your blood sugar after you eat them. The scale ranges from 1 to 100, with foods at 100 being the fastest to raise blood sugar levels.

Recent research on the GI of common fruit juices has found that orange juice has a GI of 43. Another reputable source gives orange juice a GI of 49. In either case, this puts orange juice in the low GI category.

Orange Juice vs. Whole Oranges

Whole oranges have a GI of 43, similar to and perhaps slightly lower than the GI of orange juice.

Eating a whole orange is less likely to spike your blood sugar as much as gulping down a glass of orange juice. Unlike orange juice, whole oranges contain fiber, which slows down the absorption of glucose.

One study compared the effects of eating an orange and drinking orange juice on blood sugar and found that while both increased blood sugar to a small degree, there was no significant difference between the two.

Orange Juice Nutrition

Orange juice is high in carbohydrates, vitamin C, and antioxidants, but low in fiber and protein.

A 3.5-ounce (oz) serving of orange juice contains the following:

  • Calories: 47 calories
  • Carbohydrates: 10 grams (g)
  • Protein: 0.81 g
  • Vitamin C: 30.5 milligrams (mg)
  • Fat: 0.36 g

Can You Drink Orange Juice with Diabetes?

People with diabetes have trouble regulating blood sugar and may be more susceptible to orange juice raising blood sugar, which is why they are often counseled to avoid orange juice.

However, studies on this subject are contradictory.

In one study of people with diabetes who consumed a whole orange, drank orange juice, or drank a sugar-sweetened beverage alongside a meal, blood sugar increased. However, the increase was not significantly different between groups, and each group maintained good glycemic control.

Some reports suggest that regularly drinking orange juice can increase your risk of developing diabetes, but other studies contradict this.

As a result, dietary guidelines for people with diabetes regarding orange juice and whole oranges are inconsistent. Some health professionals advise eating whole fruit instead of fruit juice, while others recommend limiting fruit juice to 150 milliliters (mL) daily, or slightly more than half a cup.

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. Murphy MM, Barrett EC, Bresnahan KA, Barraj LM. 100 % Fruit juice and measures of glucose control and insulin sensitivity: a systematic review and meta-analysis of randomised controlled trialsJ Nutr Sci. 2017;6:e59. doi: 10.1017/jns.2017.63

  2. Papandreou D, Magriplis E, Abboud M, et al. Consumption of raw orange, 100% fresh orange juice, and nectar- sweetened orange juice—effects on blood glucose and insulin levels on healthy subjectsNutrients. 2019;11(9):2171. doi:10.3390/nu11092171

  3. de Paiva A, Gonçalves D, Ferreira P, Baldwin E, Cesar T. Postprandial effect of fresh and processed orange juice on the glucose metabolism, antioxidant activity and prospective food intakeJournal of Functional Foods. 2019;52:302-309. doi: 10.1016/j.jff.2018.11.013

  4. Alhabeeb H, Sohouli MH, Lari A, et al. Impact of orange juice consumption on cardiovascular disease risk factors: a systematic review and meta-analysis of randomized-controlled trialsCritical Reviews in Food Science and Nutrition. 2022;62(12):3389-3402. doi: 10.1080/10408398.2020.1865263

  5. Robayo S, Kucab M, Walker SE, et al. Effect of 100% orange juice and a volume-matched sugar-sweetened drink on subjective appetite, food intake, and glycemic response in adultsNutrients. 2024;16(2):242. doi: 10.3390/nu16020242

  6. Verboven K, Van Ryckeghem L, Schweiggert R, et al. Acute glycaemic response of orange juice consumption with breakfast in individuals with type 2 diabetes: a randomized cross-over trialNutr Diabetes. 2025;15(1):1-6. doi:10.1038/s41387-025-00385-8

  7. MSD Manual Professional Version. Overview of nutrition.

  8. Kouadio YH, Yapo BF, Gbakayoro JB, et al. Impact of fresh orange, apple, mango and papaya fruit juices on postprandial glycemia in apparently healthy young adultsNFS Journal. 2025;38:100205. doi:10.1016/j.nfs.2024.100205

  9. MSD Manual Professional Version. Overview of nutrition – glycemic index of some foods.

  10. USDA FoodData Central. Orange juice, no pulp, not fortified, not from concentrate, refrigerated.

  11. American Diabetes Association. Miss drinking juice? Try these citrus hacks.

  12. Imamura F, O’Connor L, Ye Z, et al. Consumption of sugar sweetened beverages, artificially sweetened beverages, and fruit juice and incidence of type 2 diabetes: systematic review, meta-analysis, and estimation of population attributable fractionBr J Sports Med. 2016;50(8):496-504. doi: 10.1136/bjsports-2016-h3576rep

  13. The Diabetes and Nutrition Study Group (DNSG) of the European Association for the Study of Diabetes (EASD), Aas AM, Axelsen M, et al. Evidence-based European recommendations for the dietary management of diabetesDiabetologia. 2023;66(6):965-985. doi: 10.1007/s00125-023-05894-8

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By Sarah Bence, OTR/L

Bence is an occupational therapist with a range of work experience in mental healthcare settings. She is living with celiac disease and endometriosis.