Identification of a distinct cluster of LY6E+ macrophages in esophageal squamous cell carcinoma: functional phenotype, spatial interaction, and prognostic significance

Generation of the ESCC single-cell transcriptomic atlas To characterize the TME in ESCC, we performed ...

Diagnosed With Advanced Renal Cell Carcinoma: Why You May Want a Second Opinion, and How to Find One

Seeking out a second opinion can give you the confidence that you’re getting the best ...

Single-cell transcriptomics reveals heterogeneity and immune microenvironment in lymphatic metastasis of head and neck squamous cell carcinoma

Qin Y, Zheng X, Gao W, Wang B, Wu Y. Tumor microenvironment and immune-related therapies ...

DPP9 inhibition boosts antitumor immunity by disrupting BRISC-mediated PD-L1 expression in clear cell renal cell carcinoma

Xue G, Li X, Kalim M, Fang J, Jiang Z, Zheng N, et al. Clinical ...

Regulatory mechanisms of ALKBH5/CIITA axis in the synergistic modulation of hepatocellular carcinoma radiotherapy and immunotherapy

Cell lines and culture In this research, the human normal liver cell line LO2, along ...

Immuno-molecular features and therapeutic implications of brain metastases in clear cell renal cell carcinoma patients

We start with a case report, because it illustrates well the current challenges and possibilities ...

Overview of Libtayo, First FDA-Approved Drug for Metastatic Cutaneous Squamous Cell Carcinoma (CSCC) When Surgery or Radiation Isn’t an Option

Susan (Sue) Treiman is an award-winning newspaper reporter, television producer, website executive, and corporate communications ...