Scientists discover the switch that revives exhausted cancer-fighting T cells

Researchers from the Salk Institute for Biological Studies, UNC Lineberger Comprehensive Cancer Center, and UC ...

Exocyst complex regulates fungal-mediated IL-33 release from cancer cells

Recent studies show that mycobiomes are pervasive in tumors and play a key role in ...

Piezo1-dependent activation of stromal cells ignites muscle inflammation in exercise and injury and is associated with inflammaging

Furman, D. et al. Chronic inflammation in the etiology of disease across the life span. ...

Inhibition of cGAS in dendritic cells suppresses maturation and prolongs allograft survival in mice

Durand F, Levitsky J, Cauchy F, Gilgenkrantz H, Soubrane O, Francoz C. Age and liver ...

3 Skin Care Habits That Actually Help Your Skin Cells Act Younger

“I am a fan of LED therapy. It can help rejuvenate the skin, it can create smoothness, ...

Thromboxane receptor activation in dendritic cells mitigates sepsis by suppressing S100a8/a9-mediated neutrophil recruitment

Human participants Sepsis patients and controls were recruited at Tianjin Medical University General Hospital. Sepsis ...

Intermittent fasting evicts long-lived plasma cells from survival niche

The efficacy of vaccination and previous infection in mediating protective humoral responses depends on the ...

Phagocytosis of necroptotic cells optimizes type 1 conventional dendritic cells for induction of a cytotoxic T-cell response

Meier P, Legrand AJ, Adam D, Silke J. Immunogenic cell death in cancer: targeting necroptosis ...

Metabolic quiescence of naive-like memory T cells precedes and maintains antigen-specific T cell memory

Ethics regulations Ethics approval for the yellow fever study (number 350_20 B; clinical trial ID: ...

B cells maintain the homeostasis of splenic marginal zone antigen-presenting cells to promote the antiviral CD8+ T-cell response

Forte E, Zhang Z, Thorp EB, Hummel M. CytomegalovirUs Latency And Reactivation: An Intricate Interplay ...