CD300ld on pathologically activated neutrophils promotes tumor immune suppression by binding phosphatidylserine on CD8+ T cells

Mao, Y. et al. The landscape of objective response rate of anti-PD-1/L1 monotherapy across 31 ...

SHP1 expression in tumor-associated dendritic cells drives immunoevasion via impairing CD8+ memory T cell responses

Despite the achievements of immunotherapy in the treatment of cancer, overcoming the immune resistance is ...

CCR7 orchestrates the malignant progression of memory B cells in MYC-overexpressing lymphoma

The lymph node homing fate of memory B cells guided by CCR7 We first examined ...

Goblet cells tune ILC2 activity through a gut-specific response checkpoint | Science Immunology

Notch signaling tunes the environmental responsiveness of intestinal ILC2s. ...

Whole-protein screening and multi-modal profiling of antigen-specific CD4+ T cells at single-cell resolution

Class II SCT library enables reliable ex vivo identification of antigen-specific CD4+ T cells We previously ...

An inflammasome-driven differentiation program in intestinal stem cells protects against Salmonella infection

Ethics statement All animal experiments were approved by the Institutional Animal Care and Use Committee ...

Scientists make old blood stem cells young again in major anti-aging breakthrough

Scientists at the Icahn School of Medicine at Mount Sinai have successfully reversed aging in ...

A role for CD8+ T cells in lupus nephritis

Reporting in Immunity, Al Souz et al. provide evidence that kidney-infiltrating CD8+ T cells contribute ...

Isolated islets showing cell nuclei (blue) and three main endocrine cell types: insulin-producing beta cells (green), glucagon-producing alpha cells (red), and somatostatin-producing delta cells (white).

Tuesday, May 12, 2026 Comprehensive characterization of islet cells facilitated by national organ donation program. ...

Innate lymphoid cells in rheumatoid arthritis as mediators of pathology and resolution

Gravallese, E. M. & Firestein, G. S. Rheumatoid arthritis – common origins, divergent mechanisms. N. ...