Tag: chimeric

Synergizing hypomethylating agents with off-the-shelf CD70-targeted chimeric antigen receptor-engineered natural killer T cells for the treatment of acute myeloid leukemia

Synergizing hypomethylating agents with off-the-shelf CD70-targeted chimeric antigen receptor-engineered natural killer T cells for the treatment of acute myeloid leukemia

HMAs upregulate CD70, CD1d, and NKR ligands on AML blasts We first confirmed that HMAs ...

READ MORE
Anti-MSLN chimeric antigen receptor-like NK cell therapy with tumor-penetrating capacity (uCAR-like NK) for solid tumors

Anti-MSLN chimeric antigen receptor-like NK cell therapy with tumor-penetrating capacity (uCAR-like NK) for solid tumors

Construction and characterization of the bispecific cell engager MSLN×CD16A To construct the bispecific cell engager ...

READ MORE
Cis- and trans-binding chimeric costimulatory receptors enhance T-cell fitness and tumor control

Cis- and trans-binding chimeric costimulatory receptors enhance T-cell fitness and tumor control

Ledergor G, Fan Z, Wu K, McCarthy E, Hyrenius-Wittsten A, Starzinski A, et al. CD4+ ...

READ MORE