Tag: differentiation

An inflammasome-driven differentiation program in intestinal stem cells protects against Salmonella infection

An inflammasome-driven differentiation program in intestinal stem cells protects against Salmonella infection

Ethics statement All animal experiments were approved by the Institutional Animal Care and Use Committee ...

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Aberrant Kupffer-like differentiation of hematopoietic stem cell is critical for the MDS pathogenesis in Setd2-deficient mice

Aberrant Kupffer-like differentiation of hematopoietic stem cell is critical for the MDS pathogenesis in Setd2-deficient mice

Issa JP. The myelodysplastic syndrome as a prototypical epigenetic disease. Blood. 2013;121:3811–7. Article  PubMed  PubMed ...

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Single-cell multiomic atlas of healthy pediatric bone marrow reveals age-dependent differences in lineage differentiation driven by stromal signaling

Single-cell multiomic atlas of healthy pediatric bone marrow reveals age-dependent differences in lineage differentiation driven by stromal signaling

Human donors BM samples were obtained from three independent cohorts, each used for distinct analyses. ...

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Cohesin-mediated chromatin organization controls the differentiation and function of dendritic cells | Science Immunology

Cohesin-mediated chromatin organization controls the differentiation and function of dendritic cells | Science Immunology

Chromatin-organizing cohesin complex cooperates with transcription factor IRF8 to enable the functionality of dendritic cells ...

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The differentiation and function of heterogeneous thymic dendritic cell subsets require signals provided by distinct thymocyte cell types

The differentiation and function of heterogeneous thymic dendritic cell subsets require signals provided by distinct thymocyte cell types

Ashby, K. M. & Hogquist, K. A. A guide to thymic selection of T cells. ...

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