Monocyte-derived macrophages drive neurological tissue damage through mitochondrial reactive oxygen species | Science Immunology

Quenching mitochondrial reactive oxygen species in monocyte-derived macrophages, but not in microglia, ameliorates neuroinflammation. ...

CD1d functions as a ligand for PIRA2 to drive macrophage activation in nonalcoholic fatty liver disease

Liver inflammation is a key driver of nonalcoholic fatty liver disease (NAFLD) and its progressive ...

9 Science-Backed Tips for Increasing Your Sex Drive

Sex drive, or libido, is your general desire for sexual activity. It’s normal for libido ...

How to Lower a High Sex Drive and When to Consider It

Key Takeaways Mindfulness and meditation can help control sexual urges.  Certain medications, like antidepressants and ...

Aldehyde and seek: Toxic aldehydes drive exhaustion in tumor-infiltrating T cells | Science Immunology

Aldehydes accumulating in response to reduced fatty acid oxidation in tumor-infiltrating lymphocytes damage mitochondria and ...

STING controls glycolysis and histone lactylation to drive macrophage metabolic reprogramming in postoperative ileus

Vather, R., Trivedi, S. & Bissett, I. Defining postoperative ileus: results of a systematic review ...

B cells drive CD4 T cell immunosenescence and age-associated health decline | Science Immunology

B cells promote CD4 T cell aging and decline in health-span parameters through intercellular communication ...

A hidden immune loop may drive dangerous inflammation with age

As people grow older, the immune system often becomes less balanced and more prone to ...

Publisher Correction: SLC2A1+ tumour-associated macrophages spatially control CD8+ T cell function and drive resistance to immunotherapy in non-small-cell lung cancer

These authors contributed equally: Lei Wang, Han Chu, Degao Chen, Yuxuan Wei. Department of Oncology, ...

Structural variation tunes apoptotic responses to drive immune escape in melanoma | Science Immunology

Copy-number variation reshapes apoptotic gene dosage to drive acquired immunotherapy resistance in melanoma. ...