Targeting the OTU family: a core therapeutic strategy for reshaping the immunosuppressive microenvironment and reversing drug resistance in HCC by coordinating the autophagy-ferroptosis balance

Hepatocellular carcinoma (HCC) treatment faces dual challenges: resistance to targeted therapy and low response rates ...

Type 2 Diabetes

A new kind of experimental medication called retatrutide is yielding impressive blood sugar and weight ...

Structural basis for prostaglandin and drug transport via SLCO2A1

Cryo-EM structure of Slco2a1 To understand the structural basis for PG recognition, we determined the ...

PANoptosis as a drug discovery framework: integrating cell death architecture with clinical translation

Wang Y, Kanneganti TD. From pyroptosis, apoptosis and necroptosis to PANoptosis: a mechanistic compendium of ...

Spirituality May Protect Against Problematic Alcohol and Drug Use

While fewer Americans are drinking, those who do are drinking more — raising the risk ...

Heart Disease Drug Recalled Nationwide for Leaking That Could Reduce Potency

A drugmaker has recalled over 20,000 bottles of icosapent ethyl (IPE), a generic version of ...

Atopic Dermatitis Treatments: Drug and Nondrug Therapies

Several oral and injectable medications have also been approved to help manage atopic dermatitis symptoms ...

Breakthrough sepsis drug shows promise in human trial

Researchers at Griffith University report encouraging progress toward treating sepsis after a Phase II clinical ...

Overview of Libtayo, First FDA-Approved Drug for Metastatic Cutaneous Squamous Cell Carcinoma (CSCC) When Surgery or Radiation Isn’t an Option

Susan (Sue) Treiman is an award-winning newspaper reporter, television producer, website executive, and corporate communications ...

A simple drug pair may succeed where liver fibrosis treatments failed

Researchers have found that a pair of existing drugs is far more effective when used ...