dysfunction – Awesamo Health

Targeting CCR1-mediated macrophage phenotypic switching to alleviate bladder pain and urinary dysfunction in interstitial cystitis

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic inflammatory condition with limited treatments. Although macrophages ...

Cardiac lymphatic dysfunction and repair in cardiovascular disease

Brakenhielm, E. & Alitalo, K. Cardiac lymphatics in health and disease. Nat. Rev. Cardiol. 16, ...

Exercise alleviates cognitive dysfunction in Alzheimer’s disease mice via skeletal muscle-derived extracellular vesicles that enhance plaque clearance by microglia

Knopman, D. S. et al. Alzheimer disease. Nat. Rev. Dis. Primers 7, 33 (2021). Article ...

Prostaglandin E2 induces dendritic cell dysfunction in skin involvement of breast cancer

Elder EE, Kennedy CW, Gluch L, Carmalt HL, Janu NC, Joseph MG, et al. Patterns ...

Targeting immunometabolic pathways with AZD1656 alleviates inflammation and metabolic dysfunction in type 2 diabetic cardiomyopathy

Animals Commercially available 8-week-old T2D mice (db/db mouse, The Jackson Laboratory homozygous BKS.Cg-Dock7m +/+ Leprdb/J, ...