Tag: efficacy

De novo engineered disulfide bond supersedes native interchain linkage to enhance TCR pairing and anti-tumor efficacy in T cell therapy

De novo engineered disulfide bond supersedes native interchain linkage to enhance TCR pairing and anti-tumor efficacy in T cell therapy

Baulu E, Gardet C, Chuvin N, Depil S. TCR-engineered T cell therapy in solid tumors: ...

READ MORE
Balancing the efficacy and safety of chimeric antigen receptor T-cell therapy by affinity combination

Balancing the efficacy and safety of chimeric antigen receptor T-cell therapy by affinity combination

In vitro characterization of high- and low-affinity CAR-T cells In order to systematically explore the ...

READ MORE
IL-1 delineates squalene-based adjuvant efficacy and reactogenicity in a cell-type-specific manner

IL-1 delineates squalene-based adjuvant efficacy and reactogenicity in a cell-type-specific manner

Antigen and adjuvants Full-length recombinant SARS-CoV-2 S protein from Pango lineage A (S-910823; Ag) was ...

READ MORE
CRTAM inhibition mitigates toxicity of immune checkpoint inhibitors without antitumor efficacy trade-off

CRTAM inhibition mitigates toxicity of immune checkpoint inhibitors without antitumor efficacy trade-off

Reck, M., Remon, J. & Hellmann, M. D. First-line immunotherapy for non-small-cell lung cancer. J. ...

READ MORE
Long-term efficacy and safety of the single-dose tetravalent Butantan dengue vaccine

Long-term efficacy and safety of the single-dose tetravalent Butantan dengue vaccine

Bhatt, S. et al. The global distribution and burden of dengue. Nature 496, 504–507 (2013). ...

READ MORE
Attenuating age-related decline in dendritic cell migration improves vaccine efficacy via gut-immune crosstalk

Attenuating age-related decline in dendritic cell migration improves vaccine efficacy via gut-immune crosstalk

Lopez-Otin, C., Blasco, M. A., Partridge, L., Serrano, M. & Kroemer, G. Hallmarks of aging: ...

READ MORE
Immunogenicity and protective efficacy of MERS CoV, NL140422, and HKU4 spike protein nanoparticle vaccines

Immunogenicity and protective efficacy of MERS CoV, NL140422, and HKU4 spike protein nanoparticle vaccines

Expression and purification of S antigens DNA constructs encoding MERS-CoV England-1 S with the 2 P ...

READ MORE
Comparative efficacy of Bacillus probiotics and formalin-killed bacterin against Vibrio anguillarum in European eel elvers

Comparative efficacy of Bacillus probiotics and formalin-killed bacterin against Vibrio anguillarum in European eel elvers

Nielsen, T. & Prouzet, P. Capture-based aquaculture of the wild European eel (Anguilla anguilla). Capture-based ...

READ MORE
Comparative evaluation of 5 combination adjuvants on immunogenicity and efficacy of approved seasonal influenza vaccines

Comparative evaluation of 5 combination adjuvants on immunogenicity and efficacy of approved seasonal influenza vaccines

Influenza (Seasonal). https://www.who.int/news-room/fact-sheets/detail/influenza-(seasonal) (Accessed 17 Oct 2024). Wiley, D. C., Wilson, I. A. & Skehel, ...

READ MORE
Mesenchymal stromal cells counteract with age-related immune decline and enhance vaccine efficacy by modulating endogenous splenic marginal reticular cells in elderly models

Mesenchymal stromal cells counteract with age-related immune decline and enhance vaccine efficacy by modulating endogenous splenic marginal reticular cells in elderly models

Collier DA, Ferreira IATM, Kotagiri P, Datir RP, Lim EY, Touizer E, et al. Age-related ...

READ MORE