Scarless circular mRNA-based CAR-T cell therapy elicits superior antitumor efficacy

High-yield and scarless cmRNA synthesis via an engineered PIE First, we engineered a new PIE ...

Intraperitoneal immune microenvironment and efficacy of intraperitoneal chemotherapy in patients with gastric cancer and peritoneal metastasis

Our previous study demonstrated that intraperitoneal paclitaxel improves survival outcomes in patients with gastric cancer ...

Minor SHIV variants abrogate protective efficacy of broadly neutralizing antibodies in rhesus macaques

Animals Animal studies were conducted with the approval of the appropriate Institutional Animal Care and ...

Dual-target CAR-T therapy for ovarian cancer: synergistic targeting of MSLN and B7H3 enhances anti-tumor efficacy and overcomes antigen heterogeneity

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics ...

NIR-IIb fluorescence ratiometric imaging of tumor-associated neutrophils for immunotherapy efficacy monitoring and strategy optimization

Synthesis and characterization of NE-responsive NIR-II fluorescence probes The custom-synthesized NIR-II fluorescence dye, Bi-HCy-OH (benzo[cd]indole ...