Tag: Engineered

De novo engineered disulfide bond supersedes native interchain linkage to enhance TCR pairing and anti-tumor efficacy in T cell therapy

De novo engineered disulfide bond supersedes native interchain linkage to enhance TCR pairing and anti-tumor efficacy in T cell therapy

Baulu E, Gardet C, Chuvin N, Depil S. TCR-engineered T cell therapy in solid tumors: ...

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Influenza mRNA vaccine with engineered panhandle-forming UTRs provides potent, dose-sparing protection against seasonal influenza viruses

Influenza mRNA vaccine with engineered panhandle-forming UTRs provides potent, dose-sparing protection against seasonal influenza viruses

Influenza viruses pose a persistent threat to global public health, causing widespread respiratory illness and ...

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Engineered sialylated IgG1 Fc as a dose-sparing alternative to IVIG

Engineered sialylated IgG1 Fc as a dose-sparing alternative to IVIG

Bayry, J. et al. Intravenous immunoglobulin: mechanism of action in autoimmune and inflammatory conditions. J. ...

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Engineered extracellular vesicles reprogram T cells by targeting PD-1 and PHB1 signaling in inflammatory bowel disease

Engineered extracellular vesicles reprogram T cells by targeting PD-1 and PHB1 signaling in inflammatory bowel disease

BMI1/hypoxia-primed MSC-derived EVs exhibit enhanced immunoregulatory features and alleviate colitis symptoms in vivo To potentiate ...

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