Tag: mice

Weaning drives microbiome-mediated epigenetic regulation to shape immune memory in mice

Weaning drives microbiome-mediated epigenetic regulation to shape immune memory in mice

SPF and GF Lgr5-GFP mice We used a knock-in Lgr5EGFP−IRES−CreERT2 mouse model (Lgr5-GFP) in which ...

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Lysosome-targeting live attenuated influenza vaccines elicit robust and broad immunity in mice

Lysosome-targeting live attenuated influenza vaccines elicit robust and broad immunity in mice

Viruses and vaccines Influenza A/WSN/33 (H1N1) and A/X-31 (H3N2) viruses were used in this study. ...

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Aberrant Kupffer-like differentiation of hematopoietic stem cell is critical for the MDS pathogenesis in Setd2-deficient mice

Aberrant Kupffer-like differentiation of hematopoietic stem cell is critical for the MDS pathogenesis in Setd2-deficient mice

Issa JP. The myelodysplastic syndrome as a prototypical epigenetic disease. Blood. 2013;121:3811–7. Article  PubMed  PubMed ...

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Inhibition of cGAS in dendritic cells suppresses maturation and prolongs allograft survival in mice

Inhibition of cGAS in dendritic cells suppresses maturation and prolongs allograft survival in mice

Durand F, Levitsky J, Cauchy F, Gilgenkrantz H, Soubrane O, Francoz C. Age and liver ...

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Mechanism of Morchella polysaccharide in anti-fatigue: the role of the gut microbiota-metabolite axis in mice

Mechanism of Morchella polysaccharide in anti-fatigue: the role of the gut microbiota-metabolite axis in mice

Behrens, M. et al. Fatigue and Human Performance: An Updated Framework. Sports Med. 53, 7–31 ...

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Exercise alleviates cognitive dysfunction in Alzheimer’s disease mice via skeletal muscle-derived extracellular vesicles that enhance plaque clearance by microglia

Exercise alleviates cognitive dysfunction in Alzheimer’s disease mice via skeletal muscle-derived extracellular vesicles that enhance plaque clearance by microglia

Knopman, D. S. et al. Alzheimer disease. Nat. Rev. Dis. Primers 7, 33 (2021). Article  ...

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‘Universal vaccine’ protects mice against multiple pathogens

‘Universal vaccine’ protects mice against multiple pathogens

A macrophage — a ‘first responder’ cell in the innate immune system — in the ...

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Conserved CD4+ T cell staphylococcal and streptococcal epitopes enable broad-acting vaccines in mice

Conserved CD4+ T cell staphylococcal and streptococcal epitopes enable broad-acting vaccines in mice

GBD 2021 Antimicrobial Resistance Collaborators Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis ...

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mRNA vaccination overcomes haemozoin-mediated impairment of whole-parasite malaria vaccines in mice

mRNA vaccination overcomes haemozoin-mediated impairment of whole-parasite malaria vaccines in mice

World Health Organization World Malaria Report 2023 (World Health Organization, 2024). Putrianti, E. D., Silvie, ...

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Anhydroicaritin-loaded mesenchymal stem cell exosomes ameliorate psoriasis via ACSL4-mediated ferroptosis in mice

Anhydroicaritin-loaded mesenchymal stem cell exosomes ameliorate psoriasis via ACSL4-mediated ferroptosis in mice

Kong, Y. et al. Narciclasine inhibits phospholipase A2 and regulates phospholipid metabolism to ameliorate psoriasis-like ...

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