The strategic importance of mRNA vaccine technologies in Africa for achieving public health independence

The success of mRNA vaccines during COVID-19 indicated the feasibility of this technology for rapidly ...

Tuning the immune response to mRNA vaccines

Tuning the immune response to mRNA vaccines ...

Influenza mRNA vaccine with engineered panhandle-forming UTRs provides potent, dose-sparing protection against seasonal influenza viruses

Influenza viruses pose a persistent threat to global public health, causing widespread respiratory illness and ...

DNA origami vaccines could be the next leap beyond mRNA

The COVID-19 pandemic brought messenger RNA (mRNA) vaccines into the global spotlight. After completing clinical ...

Personalized mRNA vaccine induces strong, durable immunity in hard-to-treat breast cancer

CLINICAL BRIEFINGS 18 February 2026 In an experimental trial, a personalized mRNA vaccine was tested ...

mRNA vaccination overcomes haemozoin-mediated impairment of whole-parasite malaria vaccines in mice

World Health Organization World Malaria Report 2023 (World Health Organization, 2024). Putrianti, E. D., Silvie, ...

BCMA-directed mRNA CAR T cell therapy for myasthenia gravis: a randomized, double-blind, placebo-controlled phase 2b trial

Oversight The MG-001 part 3 trial was performed in accordance with the principles of the ...

BCMA-directed mRNA CAR-T cell therapy for myasthenia gravis: exploratory biomarker analysis of a placebo-controlled phase 2b trial

Preclinical in vitro experiments Generation of CAR cells and evaluation of CAR expression Primary CD8+ ...

Breaking barriers in prostate cancer: the mRNA vaccine breakthrough and what comes next

Bray, F. et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide ...

Zwitterionic lipid design enhances mRNA cancer vaccine efficacy and reduces reactogenicity

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