Tag: overcomes

Targeting the PSMD14-BCKDK pathway overcomes immune suppression and enhances CAR-NK infiltration in glioblastoma

Targeting the PSMD14-BCKDK pathway overcomes immune suppression and enhances CAR-NK infiltration in glioblastoma

Tumor cells outcompete NK cells for BCAA, with BCKDK as a key regulator Nutrient competition ...

READ MORE
Modulating AP-1 enables CAR T cells to establish an intratumoral stemlike reservoir and overcomes resistance to PD-1 blockade | Science Immunology

Modulating AP-1 enables CAR T cells to establish an intratumoral stemlike reservoir and overcomes resistance to PD-1 blockade | Science Immunology

c-Jun overexpression fails to prevent CAR T cell exhaustion in tumors, but PD-L1 blockade restores ...

READ MORE
mRNA vaccination overcomes haemozoin-mediated impairment of whole-parasite malaria vaccines in mice

mRNA vaccination overcomes haemozoin-mediated impairment of whole-parasite malaria vaccines in mice

World Health Organization World Malaria Report 2023 (World Health Organization, 2024). Putrianti, E. D., Silvie, ...

READ MORE
Targeting hypoxic exosomal IGFBP2 overcomes CD47-mediated immune evasion in glioblastoma

Targeting hypoxic exosomal IGFBP2 overcomes CD47-mediated immune evasion in glioblastoma

Horbinski C, Berger T, Packer RJ, Wen PY. Clinical implications of the 2021 edition of ...

READ MORE
Dual-target CAR-T therapy for ovarian cancer: synergistic targeting of MSLN and B7H3 enhances anti-tumor efficacy and overcomes antigen heterogeneity

Dual-target CAR-T therapy for ovarian cancer: synergistic targeting of MSLN and B7H3 enhances anti-tumor efficacy and overcomes antigen heterogeneity

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics ...

READ MORE