Epidermal MHC-II-mediated NK cell recruitment triggers keratinocyte pyroptosis, facilitating pathogenesis of psoriasis

MHC-II is highly expressed in psoriatic skin lesions First, our scRNA-seq analysis of epidermal samples ...

Short-, medium-, versus long-chain fatty acids: mechanisms of immunomodulation and disease pathogenesis

Kim CH. Control of lymphocyte functions by gut microbiota-derived short-chain fatty acids. Cell Mol Immunol. ...

CD70/CD27 signaling promotes the pathogenesis of multiple myeloma and represents a promising therapeutic target

Vogelsberg A, Schürch CM, Fend F. Multiples Myelom aus Sicht der Pathologie. Radiologe. 2022;62:12–19. Article  ...

Aberrant Kupffer-like differentiation of hematopoietic stem cell is critical for the MDS pathogenesis in Setd2-deficient mice

Issa JP. The myelodysplastic syndrome as a prototypical epigenetic disease. Blood. 2013;121:3811–7. Article  PubMed  PubMed ...

Valve biology and rheumatic heart disease pathogenesis

Carapetis, J. R., Steer, A. C., Mulholland, E. K. & Weber, M. The global burden ...

Interferon regulatory factor 5 involves the pathogenesis of emphysema through NLRP3 and Ly6C expressing cells

Vogelmeier, C. F. et al. Global strategy for the diagnosis, management, and prevention of chronic ...