Salmonella SopB suppresses post-transcriptionally regulated cytokine release to reduce early tissue inflammation and delay disease progression

Bacterial strains In this study, wild-type (wt) Salmonella enterica subsp. enterica serovar Typhimurium (ATCC14028, S. ...

CCR7 orchestrates the malignant progression of memory B cells in MYC-overexpressing lymphoma

The lymph node homing fate of memory B cells guided by CCR7 We first examined ...

This Vitamin May Reshape The Gut’s Response In Those With IBD

And the gut microbiome is especially responsive. It shifts based on what you eat, how ...

NINJ1 ubiquitination by TRIM72 protects against plasma membrane rupture and AKI-CKD progression

Tubule-specific deletion of Ninj1 protects against AKI-CKD progression In human patients with Acute Kidney Injury ...

C3G/IC-MPGN Progression: Can New C3 Inhibitors Stop the Path to Dialysis?

How C3 Inhibitors Work How C3 Inhibitors Work The complement system is part of your ...

Multifunctionality of TIM-3: from immunological aging to pathological progression

The aging brain experiences profound immunological and vascular changes that increase its vulnerability to both ...

ANGPTL2 inhibits macrophage pyroptosis and alleviates rheumatoid arthritis progression by regulating mitophagy via IGFBP5

Smolen JS, Aletaha D, McInnes IB. Rheumatoid arthritis. Lancet. 2016;388:2023–38. Google Scholar  Alivernini S, Firestein ...

Intracellular complement Factor H promotes tumor progression through modulation of cell cycle and actin cytoskeleton

Borisov, T., Metodiev, D., Ferdinandov, D. & Roumenina, L. T. Complement system in tumor growth ...

Histone demethylase KDM7A negatively regulates fibrotic macrophage polarization and lung fibrosis progression

Medzhitov, R. Origin and physiological roles of inflammation. Nature 454, 428–435 (2008). Google Scholar  Weiskirchen, ...

Inhibin beta A drives colorectal cancer progression through macrophage M2 polarization and mitochondria-dependent ferroptosis suppression

Ethics declarations The animal protocols received authorization from Hunan Cancer Hospital’s Institutional Animal Care and ...