Targeting the OTU family: a core therapeutic strategy for reshaping the immunosuppressive microenvironment and reversing drug resistance in HCC by coordinating the autophagy-ferroptosis balance

Hepatocellular carcinoma (HCC) treatment faces dual challenges: resistance to targeted therapy and low response rates ...

Is Oxidative Stress The Underlying Driver Of Insulin Resistance

When most people think about insulin resistance, sugar is usually the first thing that comes ...

MTA1-mediated transcriptional repression of Cox2 confers resistance against neutrophil infiltration in endometritis

Einenkel R, Zygmunt M, Muzzio DO. Microorganisms in the healthy upper reproductive tract: from denial ...

Modulating AP-1 enables CAR T cells to establish an intratumoral stemlike reservoir and overcomes resistance to PD-1 blockade | Science Immunology

c-Jun overexpression fails to prevent CAR T cell exhaustion in tumors, but PD-L1 blockade restores ...

Muscle Strength Loss Increases 70% If You're Deficient In This Vitamin

Curious whether timing of physical activity had an impact on insulin resistance, researchers assessed sedentary ...

Metabolic borders shape immune resistance

Metabolic borders shape immune resistance ...

Publisher Correction: SLC2A1+ tumour-associated macrophages spatially control CD8+ T cell function and drive resistance to immunotherapy in non-small-cell lung cancer

These authors contributed equally: Lei Wang, Han Chu, Degao Chen, Yuxuan Wei. Department of Oncology, ...