Structural variation tunes apoptotic responses to drive immune escape in melanoma | Science Immunology

Copy-number variation reshapes apoptotic gene dosage to drive acquired immunotherapy resistance in melanoma. ...

PTMA safeguards mitochondrial integrity to sustain metabolic function and antitumor activity of CD8 T cells | Science Immunology

The TCF1-PTMA axis maintains mitochondrial homeostasis to sustain CD8 T cell function and preserve immune ...

Intestinal epithelial TLR5 signaling promotes barrier-supportive macrophages | Science Immunology

Colonic stem cell TLR5 sensing of microbes promotes macrophage recruitment and maturation to support intestinal ...

Why Science Says Soup Tastes Better the Next Day

Soups taste better the next day as flavors meld and seasonings distribute evenly. Cooling, storing ...

Segmented filamentous bacteria reprogramming of alveolar macrophages limits postinfluenza bacterial pneumonia | Science Immunology

SFB colonization phenotypically alters alveolar macrophages, maintaining their antibacterial functions in inflamed interferon-rich lungs. ...

Pathogenic IgE-fated memory B cell responses retain functional plasticity | Science Immunology

Pathogenic B cell responses to allergens are reprogrammed by blockade of IL-4 and IL-13 signaling. ...

DNA-damaging chemotherapy reshapes cardiac-resident macrophage composition and function | Science Immunology

Carboplatin reshapes macrophages to protect the heart through type I IFN signaling in mouse models. ...

Could Ditching Sugar Be The Key To Aging Well? Science Weighs In

Excess sugar contributes to inflammation, oxidative stress, and DNA damage, all of which are bad ...

What Science Says About Olive Oil and Lemon Juice for Treating Health Conditions

Key Takeaways There’s no evidence to suggest you can prevent, treat, or cure illness or ...

Siglec-F+ neutrophils promote the resolution of acute lung injury through ALOX15 induction | Science Immunology

A proresolving subset of mouse tissue neutrophils expressing Siglec-F and ALOX15 accelerates resolution of lung ...