Tag: TCR

De novo engineered disulfide bond supersedes native interchain linkage to enhance TCR pairing and anti-tumor efficacy in T cell therapy

De novo engineered disulfide bond supersedes native interchain linkage to enhance TCR pairing and anti-tumor efficacy in T cell therapy

Baulu E, Gardet C, Chuvin N, Depil S. TCR-engineered T cell therapy in solid tumors: ...

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The rise of spatial TCR profiling: Emerging technologies and open challenges | Science Immunology

The rise of spatial TCR profiling: Emerging technologies and open challenges | Science Immunology

Spatial TCR profiling has the potential answers to key questions in cancer immunology, but challenges ...

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Single-cell TCR mapping reveals spatially coordinated T cell states in head and neck cancer | Science Immunology

Single-cell TCR mapping reveals spatially coordinated T cell states in head and neck cancer | Science Immunology

Single-cell spatial TCR profiling reveals coordination of T cell phenotype and location in the tumor ...

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The TCR in CAR T cell therapy: use it or lose it?

The TCR in CAR T cell therapy: use it or lose it?

Goyco Vera D, Waghela H, Nuh M, Pan J, Lulla P. Approved CAR-T therapies have ...

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Tissue-restricted secondary TCR engagement drives the transition from stem-like to CD200+ Egr2hi arthritogenic Th17 cells

Tissue-restricted secondary TCR engagement drives the transition from stem-like to CD200+ Egr2hi arthritogenic Th17 cells

McGeachy, M. J., Cua, D. J. & Gaffen, S. L. The IL-17 family of cytokines ...

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