Deep peptide recognition profiling decodes TCR specificity and enables disease-associated antigen discovery

Selection of TCRs The 16 disease-derived TCRs analyzed in this study were previously obtained and ...

De novo engineered disulfide bond supersedes native interchain linkage to enhance TCR pairing and anti-tumor efficacy in T cell therapy

Baulu E, Gardet C, Chuvin N, Depil S. TCR-engineered T cell therapy in solid tumors: ...

The TCR in CAR T cell therapy: use it or lose it?

Goyco Vera D, Waghela H, Nuh M, Pan J, Lulla P. Approved CAR-T therapies have ...

Tissue-restricted secondary TCR engagement drives the transition from stem-like to CD200+ Egr2hi arthritogenic Th17 cells

McGeachy, M. J., Cua, D. J. & Gaffen, S. L. The IL-17 family of cytokines ...