CD300ld on pathologically activated neutrophils promotes tumor immune suppression by binding phosphatidylserine on CD8+ T cells

Mao, Y. et al. The landscape of objective response rate of anti-PD-1/L1 monotherapy across 31 ...

SHP1 expression in tumor-associated dendritic cells drives immunoevasion via impairing CD8+ memory T cell responses

Despite the achievements of immunotherapy in the treatment of cancer, overcoming the immune resistance is ...

A role for CD8+ T cells in lupus nephritis

Reporting in Immunity, Al Souz et al. provide evidence that kidney-infiltrating CD8+ T cells contribute ...

In vivo reprogramming of cytotoxic effector CD8 T cells via fractalkine-conjugated mRNA-LNPs | Science Immunology

Fractalkine-conjugated mRNA-LNPs effectively target cytotoxic effector CD8 T cells for transient in vivo reprogramming. ...

DGAT1 mediates sex-specific CD8+ T cell antitumour responses

McLane, L. M., Abdel-Hakeem, M. S. & Wherry, E. J. CD8 T cell exhaustion during ...

RUNX phosphorylation specifies CD8+ T cell lineage during positive selection

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and ...

B cells maintain the homeostasis of splenic marginal zone antigen-presenting cells to promote the antiviral CD8+ T-cell response

Forte E, Zhang Z, Thorp EB, Hummel M. CytomegalovirUs Latency And Reactivation: An Intricate Interplay ...

Phosphorylation of Runx protein controls helper CD4+ T cell versus cytotoxic CD8+ T cell lineage choice

Mice Runx1+/WRPW embryos were generated by incorporation single-strand donor DNA into the Runx1 locus by ...

Antigen specificity of clonally enriched CD8+ T cells in multiple sclerosis

Study participants A total of 18 individuals were enrolled in the study—11 with relapsing-remitting MS, ...

Cancer-associated fibroblasts (CAFs) derived from MFAP2 promote CRC proliferation and metastasis while suppressing CD8+ T cell-mediated antitumor immunity

Siegel RL, Wagle NS, Cercek A, Smith RA, Jemal A. Colorectal cancer statistics, 2023. CA ...