Bispecific T cell engagers for treatment-refractory autoimmune connective tissue diseases

Patient characteristics at baseline All patients with ASyS and SSc were treated at the University ...

Phosphorylation of Runx protein controls helper CD4+ T cell versus cytotoxic CD8+ T cell lineage choice

Mice Runx1+/WRPW embryos were generated by incorporation single-strand donor DNA into the Runx1 locus by ...

Conserved CD4+ T cell staphylococcal and streptococcal epitopes enable broad-acting vaccines in mice

GBD 2021 Antimicrobial Resistance Collaborators Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis ...

Beyond the canon: emerging modalities of regulated cell death

The field of regulated cell death (RCD) has expanded in punctuated bursts—from apoptosis and necroptosis ...

The dark side of the dot: How melanosomes dim T cell activity | Science Immunology

Melanoma cells evade immune detection by secreting MHC-peptide–loaded melanosomes that interact with and impair CD8+ ...

Mechanotransduction through T cell receptors: consensus, controversies and future outlooks

Palucka, K. & Banchereau, J. Dendritic cells: a link between innate and adaptive immunity. J. ...

Structural mechanism of anti-MHC-I antibody blocking of inhibitory NK cell receptors in tumor immunity

Margulies, D. H., Natarajan, K., Rossjohn, J. & McCluskey, J. in Paul’s Fundamental Immunology (eds. ...

B cells drive CD4 T cell immunosenescence and age-associated health decline | Science Immunology

B cells promote CD4 T cell aging and decline in health-span parameters through intercellular communication ...

Overview of Libtayo, First FDA-Approved Drug for Metastatic Cutaneous Squamous Cell Carcinoma (CSCC) When Surgery or Radiation Isn’t an Option

Susan (Sue) Treiman is an award-winning newspaper reporter, television producer, website executive, and corporate communications ...