Tag: cell

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment

Study design This study aimed to evaluate whether organelle inheritance controls CD8+ T cell differentiation. ...

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Regulation of T cell exhaustion and stemness: molecular mechanisms and implications for cancer immunotherapy

Regulation of T cell exhaustion and stemness: molecular mechanisms and implications for cancer immunotherapy

Kaech SM, Tan JT, Wherry EJ, Konieczny BT, Surh CD, Ahmed R. Selective expression of ...

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Dietary restriction reprograms CD8+ T cell fate to enhance anti-tumour immunity and immunotherapy responses

Dietary restriction reprograms CD8+ T cell fate to enhance anti-tumour immunity and immunotherapy responses

Ethical compliance All research described in this study was conducted in accordance with relevant institutional ...

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Sugar-coated CAR T for sweeter cell therapies | Science Immunology

Sugar-coated CAR T for sweeter cell therapies | Science Immunology

Deletion of the SPPL3 sheddase improves allogeneic CAR T cell persistence. ...

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Single cell mapping identifies a distinct platelet-phenotype in psoriatic type III inflammation

Single cell mapping identifies a distinct platelet-phenotype in psoriatic type III inflammation

Human samples Participants were included after written informed consent, and no compensation was provided. Sex ...

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