Interferon regulatory factor 5 involves the pathogenesis of emphysema through NLRP3 and Ly6C expressing cells

Vogelmeier, C. F. et al. Global strategy for the diagnosis, management, and prevention of chronic ...

The development of innate lymphoid cells

Robinette, M. L. & Colonna, M. Immune modules shared by innate lymphoid cells and T ...

Differential immune- and apoptosis-related gene signatures in pancreatic alpha and beta cells contribute to their fate in type 1 diabetes

Collection of raw scRNA-seq data For the human islets datasets, raw scRNA-seq FASTQ files (10X ...

B cells drive CD4 T cell immunosenescence and age-associated health decline | Science Immunology

B cells promote CD4 T cell aging and decline in health-span parameters through intercellular communication ...

A tolerogenic role for transitional dendritic cells in inflammation and cancer

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and ...

TSLP promotes GATA3-expressing effector regulatory T cells via DC2 derived from transitional DCs

Cheru, N., Hafler, D. A. & Sumida, T. S. Regulatory T cells in peripheral tissue ...

CXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting

CXCR4 marks CD4+ memory T cells associated with AML remission To identify features linked to ...

IL-21 mediates crosstalk between T cells and NK cells during the remission of type 1 diabetes

Grattoni, A. et al. Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and ...

Unraveling CD8 lineage decisions reveals that functionally distinct CD8+ T cells are selected by different MHC-I thymic peptides

Littman, D. R. How thymocytes achieve their fate. J. Immunol. 196, 1983–1984 (2016). Article  PubMed  ...

BACH2 dosage establishes the hierarchy of stemness and fine-tunes antitumor immunity in CAR T cells

Mice Male and female C57BL/6J (B6, strain 000664), B6.SJL-Ptprca Pepcb/BoyJ (B6 CD45.1, strain 002014) and ...