New Study Shows Brain Sugar Levels Help Control Myelin Formation

Most of us know the all-too-familiar brain fog that comes from skipping meals or after ...

Tetrameric STAT5 regulates the formation of immune niche cells to protect stem cell regenerative repair against mucosal inflammation

IBD–UC increased colonic crypt TCRγδ+STAT5+ T cells Using FACS analysis, we examined PBMCs from n = 24 ...

Lipid asymmetry disruption by XKR8 orchestrates neutrophil extracellular trap formation and inhibits fungal infection

Mice All mice used in this study were of the C57BL/6 genetic background. Experiments were ...

Sparcl1 mitigates abdominal aortic aneurysm through inhibiting lymphangiogenesis-mediated TLS formation

Sakalihasan, N., Limet, R. & Defawe, O. D. Abdominal aortic aneurysm. Lancet 365, 1577–1589 (2005). ...

STAT1 signaling controls cholesterol metabolism in epithelial cells and RSV-induced syncytia formation

Biallelic Knockout of STAT1 alters cellular cholesterol metabolism and homeostasis For the generation of a ...

The long noncoding RNA AC093895.1 promotes ovarian cancer formation and metastasis through a positive feedback network dependent on the transcription factor SOX4

Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, et al. Global ...

CXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting

CXCR4 marks CD4+ memory T cells associated with AML remission To identify features linked to ...

Novel anti-ITGA4 monoclonal antibody induces cell death via large pore formation in NK/T-cell lymphoma cells

Shiravand, Y. et al. Immune checkpoint inhibitors in cancer therapy. Front. Oncol. 12, 1234–1245 (2022). ...

Streptococcus gordonii type VII secretion system substrate EsxA induces neutrophil extracellular trap formation in infective endocarditis

Ethics statement All study participants provided written informed consent allowing use of human blood samples ...