Epidermal growth factor receptor controls sex differences in lung type 2 responses to inhaled allergen | Science Immunology

Female mice have exacerbated, EGFR-dependent lung type 2 immunity when exposed to inhaled house dust ...

Structural variation tunes apoptotic responses to drive immune escape in melanoma | Science Immunology

Copy-number variation reshapes apoptotic gene dosage to drive acquired immunotherapy resistance in melanoma. ...

PTMA safeguards mitochondrial integrity to sustain metabolic function and antitumor activity of CD8 T cells | Science Immunology

The TCF1-PTMA axis maintains mitochondrial homeostasis to sustain CD8 T cell function and preserve immune ...

Intestinal epithelial TLR5 signaling promotes barrier-supportive macrophages | Science Immunology

Colonic stem cell TLR5 sensing of microbes promotes macrophage recruitment and maturation to support intestinal ...

Biochemical signals from the extracellular matrix in inflammation and tumour immunology

Ligorio, C. & Mata, A. Synthetic extracellular matrices with function-encoding peptides. Nat. Rev. Bioeng. 1, ...

Macrophages conquer the glands | Nature Immunology

Mass, E., Nimmerjahn, F., Kierdorf, K. & Schlitzer, A. Nat. Rev. Immunol. 23, 1–17 (2023). ...

Segmented filamentous bacteria reprogramming of alveolar macrophages limits postinfluenza bacterial pneumonia | Science Immunology

SFB colonization phenotypically alters alveolar macrophages, maintaining their antibacterial functions in inflamed interferon-rich lungs. ...

Pathogenic IgE-fated memory B cell responses retain functional plasticity | Science Immunology

Pathogenic B cell responses to allergens are reprogrammed by blockade of IL-4 and IL-13 signaling. ...

The immunology of vitiligo | Nature Reviews Immunology

Bohm, M. et al. Vitiligo — a disease: a position paper on stigmatization, life quality ...

DNA-damaging chemotherapy reshapes cardiac-resident macrophage composition and function | Science Immunology

Carboplatin reshapes macrophages to protect the heart through type I IFN signaling in mouse models. ...