Siglec-F+ neutrophils promote the resolution of acute lung injury through ALOX15 induction | Science Immunology

A proresolving subset of mouse tissue neutrophils expressing Siglec-F and ALOX15 accelerates resolution of lung ...

CD27 agonism enhances long-lived CD4 T cell vaccine responses critical for antitumor immunity | Science Immunology

CD27 agonism enhances vaccine-induced CD4 T cell responses, enabling durable antitumor immunity not entirely dependent ...

Divergent immune responses to commensal bacteria bearing distinct motility signatures | Science Immunology

Motile commensal bacteria that induce immune hyperactivation and colon inflammation are identified. ...

Human OCEL1 senses bacterial infection to unlock inflammatory responses | Science Immunology

Detection of bacteria by human OCEL1 triggers its proteasomal degradation, resulting in increased NF-κB signaling ...

Erratum for the Review “The immunology of brain tumors” by L. Bunse et al. | Science Immunology

In the Review “The immunology of brain tumors” by L. Bunse et al., the following ...

Heterogeneity of the intestinal mononuclear phagocyte compartment in health and inflammatory bowel disease | Science Immunology

Single-cell transcriptomics resolves mononuclear phagocyte diversity in the human intestine in health and inflammatory bowel ...

Hypoxia-induced EGR1 remodels neutrophils to suppress antitumor immunity | Science Immunology

Hypoxia-induced expression of the zinc-finger transcription factor EGR1 drives immunosuppression in tumor-infiltrating neutrophils. ...

Smart chains: Designer antibodies shaped by AI | Science Immunology

Antibodies against specific epitopes were designed with assistance from artificial intelligence. ...

AI immunologists are here: Are they ready for prime time? | Science Immunology

AI-based tools can help immunologists with a range of tasks but have limitations. ...

Sugar-coated CAR T for sweeter cell therapies | Science Immunology

Deletion of the SPPL3 sheddase improves allogeneic CAR T cell persistence. ...