Salmonella SopB suppresses post-transcriptionally regulated cytokine release to reduce early tissue inflammation and delay disease progression

Bacterial strains In this study, wild-type (wt) Salmonella enterica subsp. enterica serovar Typhimurium (ATCC14028, S. ...

Fermented Foods & Inflammation Benefits May Shift After Age 65

Fermented foods have earned their reputation as gut health superstars. The probiotics, postbiotics, and bioactive ...

This Vitamin  May Help “Retrain” The Immune System In Gut Inflammation

You’re probably not getting enough of it. ...

Serum CCL1 discriminates infectious and sterile systemic inflammation in sepsis and acute pancreatitis

Rudd, K. E. et al. Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis ...

Hyperactivation of the cGAS-STING pathway promotes liver inflammation in Down syndrome

Mai CT, Isenburg JL, Canfield MA, Meyer RE, Correa A, Alverson CJ, et al. National ...

Tetrameric STAT5 regulates the formation of immune niche cells to protect stem cell regenerative repair against mucosal inflammation

IBD–UC increased colonic crypt TCRγδ+STAT5+ T cells Using FACS analysis, we examined PBMCs from n = 24 ...

Macrophage-derived MBL restrains coronavirus-induced pulmonary inflammation by modulating metabolic regulator PKM2-mediated NLRP3 activation

The precise mechanisms governing innate immune response to coronaviruses remain elusive. Our study reveals that ...

Resolvin D1 requires TLR2-FPR2 crosstalk for inflammation resolution and protection during ocular bacterial infection

Callegan, M. et al. Bacterial endophthalmitis: therapeutic challenges and host-pathogen interactions. Prog. Retin Eye Res. ...

Chronic inflammation leaves long-lasting impression on gut stem cells, increasing colorectal cancer risk

Wednesday, March 25, 2026 NIH-funded animal study finds heritable memories of damage persisted in cells ...

Mechanistic impasses: tofacitinib treatment ameliorates GM-CSF-driven macrophage inflammation

Satoeya N, Zack SR, Zoubi OA, Umar S, Burgos A, Abdulrab S, et al. Tofacitinib ...