Tetrameric STAT5 regulates the formation of immune niche cells to protect stem cell regenerative repair against mucosal inflammation

IBD–UC increased colonic crypt TCRγδ+STAT5+ T cells Using FACS analysis, we examined PBMCs from n = 24 ...

Divergent ILC3 responses to PDGF-D control mucosal immunity | Science Immunology

PDGF-D engages PDGFRβ in mice and NKp44 in humans to drive ILC3 responses. ...

Harnessing mucosal immunity for protective vaccines

Thompson, M. G. et al. Effectiveness of Covid-19 vaccines in ambulatory and inpatient care settings. ...

Distinct spatial organization governs oral mucosal immunity

Human participant and clinical study details Human volunteer recruitment and ethics approval Volunteers were prospectively ...

Recombinant Bacillus subtilis spores expressing SARS-CoV-2 spike protein induced humoral, mucosal, and cellular immunity in mice

Construction and expression of recombinant B. subtilis The plasmid pHPS9-Prom-S1.1-Term, consisting of the SARS-CoV-2 spike ...