RUNX phosphorylation specifies CD8+ T cell lineage during positive selection

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This is a summary of: Ogawa, C. et al. Phosphorylation of Runx protein controls helper CD4⁺ T cell versus cytotoxic CD8⁺ T cell lineage choice. Nat. Immunol. https://doi.org/10.1038/s41590-026-02441-6 (2026).