Scientists solve a major roadblock holding back cancer cell therapy

For the first time, researchers at the University of British Columbia have shown how to ...

Fine-tuning BACH2 dosage balances stemness and effector function to enhance antitumor T cell therapy

BACH2 overexpression locks T cells in a quiescent ineffective state We and others have shown ...

Exercise May Be Just As Effective at Relieving Depression As Medication and Therapy

Movement is medicine: It can strengthen your bones and muscles, help your heart, and boost ...

BCMA-directed mRNA CAR T cell therapy for myasthenia gravis: a randomized, double-blind, placebo-controlled phase 2b trial

Oversight The MG-001 part 3 trial was performed in accordance with the principles of the ...

BCMA-directed mRNA CAR-T cell therapy for myasthenia gravis: exploratory biomarker analysis of a placebo-controlled phase 2b trial

Preclinical in vitro experiments Generation of CAR cells and evaluation of CAR expression Primary CD8+ ...

A Therapy Tool for Memory Care Patients

I’ve seen several robots at the Consumer Electronics Show (CES), some cute and cuddly, others ...

What Is IV Nutritional Therapy, and Should You Try It?

When Mara Landis came down with the flu in 2017, no remedy seemed to work. ...

Scarless circular mRNA-based CAR-T cell therapy elicits superior antitumor efficacy

High-yield and scarless cmRNA synthesis via an engineered PIE First, we engineered a new PIE ...

Anti-MSLN chimeric antigen receptor-like NK cell therapy with tumor-penetrating capacity (uCAR-like NK) for solid tumors

Construction and characterization of the bispecific cell engager MSLN×CD16A To construct the bispecific cell engager ...

Oncolytic adenovirus delivery of neoantigens sensitizes low-mutation tumors to anti-PD-1 therapy and prevents metastasis

Cell culture C57BL/6 mice derived from the melanoma cell line B16F10, the colon cancer cell ...